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In this article Susan Mallett and Neil Barclay discuss the molecular and functional features of a new superfamily of membrane proteins defined by the presence of cysteine-rich motifs originally identified in the low-affinity nerve growth factor receptor. This superfamily includes two lymphocyte proteins of unknown function and two receptors for tumor necrosis factor.

Original publication

DOI

10.1016/0167-5699(91)90033-P

Type

Journal

Immunol Today

Publication Date

07/1991

Volume

12

Pages

220 - 223

Keywords

Amino Acid Sequence, Animals, Humans, Membrane Proteins, Molecular Sequence Data, Nerve Growth Factors, Receptors, Cell Surface, Receptors, Nerve Growth Factor, Receptors, Tumor Necrosis Factor, Sequence Homology, Nucleic Acid, Tumor Necrosis Factor-alpha