ECRAID-Prime

European Clinical Research Alliance on Infectious Diseases - PRIMary care adaptive platform trial for pandemics and Epidemics

Background and Study Aims

Respiratory infections - such as COVID-19, flu, and others - are caused by viruses and bacteria that affect the lungs and airways.

During the COVID-19 pandemic, large hospital-based studies helped discover treatments that saved many lives. But there are far fewer chances for people outside hospitals to take part in research that could find treatments to help people recover faster and avoid hospital care altogether.

ECRAID-Prime is a major study taking place in 12 European countries. It will test how safe and effective different medicines are for treating respiratory infections in adults. The goal is to find treatments that:

Help people get better more quickly

Make symptoms less severe

Reduce the need for hospital care

Stop infections spreading to family members

If after reading this information you would like to take part in this study, please follow this link to complete some questions that will help us to see if you might be eligible:

ECRAID-Prime initial contact form – Fill out form

Logo reading 'ECRAID-Prime"

Trial status: Recruiting

Contact Details

Email:

ecraid-prime@phc.ox.ac.uk

Phone:

0800 138 0880

Participant Information Documents

Click here to download the ECRAID Prime Participant Information Sheet.

Who can participate?

To be eligible to participate, you will need to be:

18 years of age or older
Experiencing symptoms of a respiratory infection such as runny nose, sore throat, cough, tiredness, headache and/or high temperature/fever
Symptoms started in the past 2-3 days

We are currently recruiting in the UK. Other countries also recruiting include France, Germany, Belgium, Ireland, Poland, Spain, and Georgia.

What does the study involve?

Participating is easy. Your GP will take a combined throat/nose swab or you will take a self-swab, which we can use to find out what is causing your respiratory infection.

If you participate, you will be randomised (allocated purely by chance) to receive:

A medical product in addition to usual care.
A control product in addition to usual care.
The usual care alone.

Additionally, you will receive instructions on how and for how long to use the medical product (if you are randomised to receive one), combined throat/nose swabs to self-swab at day 0 and day 4 and a diary.

If you participate, you will be asked to:

Take the medical product according to instructions (if you are randomised to receive a medical product.
Complete the diary at the end of each day for 28 days.
Take a combined throat/nose self-swab at day 0 and day 4.
Answer questions by phone or online after 3 months.

You will receive a £20 voucher as a thank you for your contribution.