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The PRINCIPLE trial has been highly commended at the Health Data Research UK Awards for the way in which patient data is utilised so participants are contacted about the trial soon after receiving a positive test result.

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PRINCIPLE was recognised by the judges of the Impact of the Year Award as a leading example of the innovative use of primary care data and settings whilst working at pace and scale.

The novel, collaborative approach developed by the trial and its NHS partners relies on utilising COVID-19 test result data in a secure and ethical way to ensure eligible participants across the country are contacted about the trial within 24-48 hours of receiving a positive result.

The approach means the PRINCIPLE team are now able to offer potential treatments to suitable participants earlier than if they had found the trial themselves following a recommendation from their clinician. In addition, gaining unique access to a patient Summary Care Record means the trial team can quickly verify that it is safe for each participant to join the trial.

This approach has vastly improved the rate at which eligible patients are recruited into PRINCIPLE and helping the trial platform to become the world’s largest of COVID-19 treatments for recovery at home.

Commenting, Dr Emma Ogburn, Director of Operations for the Primary Care Clinical Trials Unit, said “Last year we needed to rapidly speed up recruitment into PRINCIPLE in such a way that we were getting the right types of patients – those who had only just received a positive COVID-19 test . This group weren’t finding us in the numbers we had hoped. The new approach we developed with Health Data Research UK and our NHS partners has vastly improved uptake, it’s compliant with data privacy laws, and means that more eligible people with COVID-19 can join the trial and help in our search for treatments for recovery at home.”

The award was won by the RECOVERY trial of COVID-19 treatments for hospitalised patients.

Read more about how PRINCIPLE uses patient data here


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