The PRINCIPLE Trial
Evaluating potential treatments for COVID-19 in older people.
Join online (England, Wales & NI)
Complete our straightforward screening questionnaire to see if you are eligible to join the PRINCIPLE trial.
Join online (Scotland)
Complete our straightforward screening questionnaire to see if you are eligible to join the PRINCIPLE trial. This is the link for those in Scotland.
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![]() | What is a continuous / persistent cough?A new, continuous cough means coughing a lot for more than an hour, or 3 or more coughing episodes in 24 hours (if you usually have a cough, it may be worse than usual). |
![]() | How do I tell if I have a high temperature without a thermometer?A high temperature means you feel hot to touch on your chest or back (you do not need to measure your temperature). |
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Its really rewarding and exciting to be part of a trial where we are asking the general public to help find potential covid-19 treatments that will inform the world – no face to face visits are needed, just internet access and participant packs will be couriered to you at home. For more support, in addition to our clinical study team being at the end of the phone, your GP practice will also be aware of the study and can discuss it with you.
Dr Emma Ogburn -Director or Operations PCCTU
Further information
The Participant Information Sheet provides further details about this trial.
Find translated versions of the Participant Information Sheet here.
You can also telephone the study team on 0800 138 0880 ask questions and for further information
If your GP practice is participating, you are welcome to contact your GP first to discuss your suitability for joining the trial. Click on the link below to see if you GP practice is participating. If your GP practice is not participating, you can still call the study team using the number above, and join the study here.
Join the trial online
There are several steps to joining the trial and the first is answering a few questions to assess your eligibility.
EudraCT number: 2020-001209-22 • ISRCTN registry: ISRCTN86534580 • REC number: 20/SC/058 • IRAS number: 281958