Ph.D. BSc(Hons), PGCert
Senior Research Fellow
I am a Population Health Scientist with interests in blood pressure management and cardiovascular disease prevention in Primary Care. In particular, I am interested in how we can improve the targeting of anti-hypertensive treatments at patients with the most to gain, using risk prediction models which utilise clinical data collected routinely in Primary Care.
I lead the PRedicting Out-of-OFfice Blood Pressure in the clinic (PROOF-BP) study which looks to improve the targeting of 24hr ambulatory blood pressure monitoring in patients with suspected hypertension. I am also Co-chief Investigator on the OPTiMISE trial which aims to examine whether antihypertensive medication can be safely reduced in multi-morbid frail elderly patients with well controlled blood pressure.
My research is mainly quantitative, and includes risk prediction modelling, epidemiology, clinical trials, systematic reviews and health economics. I come from a basic science background and completed a PhD in Cardiorespiratory Physiology in 2010, but have since worked in academic Primary Care, previously at the University of Birmingham. I teach on the Evidence Based Medicine MSc degree programme and am part of the organising committee for the British and Irish Hypertension Society Young Investigator Network.
Benefits and harms of antihypertensive treatment for low risk mild hypertension: a real world, matched cohort study of over 38,000 adults
Sheppard JP. et al, (2018), Jama internal medicine
Prospective external validation of the Predicting Out-of-OFfice Blood Pressure (PROOF-BP) strategy for triaging ambulatory monitoring in the diagnosis and management of hypertension: an observational cohort study
Sheppard JP. et al, (2018), Journal of human hypertension, 32, 708 - 708
Mcmanus RJ. et al, (2017), Bmj open
Tucker KL. et al, (2017), Plos medicine, 14, e1002389 - e1002389
A comparison of blood pressure in community pharmacies with ambulatory, home and general practitioner office readings: systematic review and meta-analysis
Albasri A. et al, (2017), Journal of hypertension