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research studies




James Sheppard

Ph.D. BSc(Hons), PGCert

Senior Research Fellow

I am a Population Health Scientist with interests in blood pressure management and cardiovascular disease prevention in Primary Care. In particular, I am interested in how we can improve the targeting of anti-hypertensive treatments at patients with the most to gain, using risk prediction models which utilise clinical data collected routinely in Primary Care.

I lead the PRedicting Out-of-OFfice Blood Pressure in the clinic (PROOF-BP) study which looks to improve the targeting of 24hr ambulatory blood pressure monitoring in patients with suspected hypertension. I am also Co-chief Investigator on the OPTiMISE trial which aims to examine whether antihypertensive medication can be safely reduced in multi-morbid frail elderly patients with well controlled blood pressure.

My research is mainly quantitative, and includes risk prediction modelling, epidemiology, clinical trials, systematic reviews and health economics. I come from a basic science background and completed a PhD in Cardiorespiratory Physiology in 2010, but have since worked in academic Primary Care, previously at the University of Birmingham. I teach on the Evidence Based Medicine MSc degree programme and am part of the organising committee for the British and Irish Hypertension Society Young Investigator Network.