SNAP2: Optimising the management of blood pressure following hypertensive pregnancy to reduce cardiovascular risk
NIHR Collaboration for Leadership in Applied Health Research and Care Oxford
Planned study period: January 2024 – July 2026
Background and study aims
To develop and test the clinical and cost-effectiveness of an intervention to support self-management of antihypertensive medication following a hypertensive pregnancy. The intervention aims to improve long-term BP control and therefore reduce adverse cardiovascular outcomes and the associated costs to the NHS.
Who can participate?
Women in the postnatal period, requiring antihypertensive treatment
What does the study involve?
The intervention involves BP self-monitoring using a validated blood pressure monitor and self-titration of antihypertensive therapy guided by digital intervention, overseen by a supervising clinician.
What are the possible risks and benefits of participating?
During the trial, participants will continue to receive usual care regardless of randomisation group. As such we anticipate that the potential risks are low. Particular issues include a participant obtaining an excessively high or low BP reading in the self-monitoring and the possibility of increased anxiety due to the study.
We aim to minimise any potential risks due to poor blood pressure control by ensuring women have clear advice regarding when to seek urgent medical help.
Potential benefits for individuals taking part include better information about their BP and possible better control of blood pressure.
Professor Lucy Yardley (University of Bristol)
Professor Debra Bick (University of Warwick)
Professor Jenny Myers (University of Manchester)
Professor Lucy Chappell (King’s College London)
Professor Christine McCourt (City, University of London)
Dr Lucy Mackillop (Oxford University Hospitals Foundation Trust)
Marcus Green (Action on Pre-eclampsia Limited)
Sandra Igwe (The Motherhood Group Limited)